The Multinational Influenza
Seasonal Mortality Study (MISMS) is an international collaborative
effort to analyze national and global mortality patterns associated
with influenza virus circulation.
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MISMS has 4 specific aims:
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- To describe synchrony in seasonal
variations of various causes of mortality associated with
influenza, by state, country, and region .
- To describe long-term temporal trends
and inter-annual variations in influenza mortality patterns,
both within and amongst countries, and their association
with changes in circulating subtypes of influenza virus,
antigenic characteristics, population factors, and vaccine
coverage.
- To explore the seasonal patterns
and burden of influenza mortality in tropical countries,
and understand the global circulation of influenza viruses
- to achieve this goal, new methods for estimating mortality
impact in tropical countries need to be developed.
- To develop a world map of influenza mortality burden and seasonal patterns.
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MISMS
Progress-to-date
Detailed protocol distributed; data received from 12
countries, 15 pending; >45 published manuscripts
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