The Fogarty International Center of the U.S. National Institutes of Health (NIH) is planning an influenza research workshop at Estelar Hotel Miraflores in Lima, Peru, June 25-28, 2012. This will be the eleventh regional meeting held as part of the FIC-initiated Multinational Influenza Seasonal Mortality Study (MISMS), an international research collaboration that analyzes epidemiologic and phylogenetic patterns associated with influenza virus circulation. Past meetings/workshops have been held at the NIH and in the Americas (USA, Argentina), Asia (Nepal, China, and Vietnam), Europe (Portugal and Denmark), Africa (Senegal), and Oceania (Australia). These meetings are designed to help build analytical capacity for epidemiologic and molecular studies of influenza, identify potential collaborators, and disseminate new scientific findings that may serve to inform influenza control strategies. More information about previous meetings can be found here.
This meeting/workshop is intended for public health officials, epidemiologists, biostatisticians, and virologists who conduct research on influenza and other respiratory diseases in Latin America. Participants will also have a forum to discuss reports of influenza disease burden in populations similar to their own, as well as the opportunity to review and evaluate their data utilizing new analytical techniques and phylogenetics methodologies.
The first two days of the meeting (June 25-26) will feature scientific presentations by MISMS collaborators and meeting participants on influenza research methodologies and the dissemination of results. Topics of interest include influenza epidemiology, transmission dynamics, phylogenetic and molecular analyses, virus surveillance, disease burden, control strategies, and other public health issues.
The last two days of the meeting (June 27-28) will consist of a technical workshop during which MISMS staff will assist collaborators with the analysis of their own influenza data. This free workshop is open to those interested in the mathematical and statistical modeling of epidemiologic and virologic data, as well as the analysis of phylogenetic and antigenic data.
More information about the the schedule of events and hotel room options will be available shortly. If you have any questions about this workshop or about the MISMS Research Initiative, please do not hesitate to contact us at ficmisms@mail.nih.gov.
Visa Information: http://peru.visahq.com/
Information on vaccinations and other safety advice: http://wwwnc.cdc.gov/travel/destinations/peru.htm
Health and safety in Lima: http://www.tripadvisor.com/Travel-g294316-s206/Lima:Peru:Health.And.Safety.html
Etiquette: http://www.tripadvisor.com/Travel-g294311-s606/Peru:Tipping.And.Etiquette.html
http://www.expatperu.com/peruvian-manners-and-etiquette.html
Final Agenda Summary
(Times are approximate)
Day
1 - Monday, June 25: Scientific presentations
8:30am – 9:00 am Registration
9:00am – 10:10 pm Session I: Welcome and MISMS overview
9:00 – 9:25 am Mark Miller, Fogarty International Center (FIC), NIH, USA: Welcome and MISMS overview.
9:25 – 9:50 am Eric Halsey, NAMRU-6, Peru: An overview of NAMRU-6's international respiratory surveillance network.
9:50 – 10:15 am Wladimir Alonso, FIC, NIH, USA: Epidemiology of influenza in the tropics: The case of Brazil.
10:15 – 10:45 am Coffee Break
10:45 am – 12:00 pm Session II: 2009 Pandemic influenza in the Americas: Lessons learned
10:45 – 11:00am Jorge Gomez, Epidemiology General Directorate (DGE) of the Peruvian Ministry of Health, Peru: Lessons learned from the 2009 pandemic in Peru.
11:00 – 11:15 am Gerardo Chowell, Arizona State University and FIC, NIH, USA: Transmission dynamics of the 2009 A/H1N1 influenza pandemic using high resolution surveillance data.
11:15 – 11:30 am Fernanda Moura, Universidade Federal do Ceará, Brazil: Influenza in an equatorial city: Something else about the more recent influenza pandemic in Brazil.
11:30 – 11:45 am Maria de Lourdes Oliveira, Oswaldo Cruz Institute, National Reference Laboratory for Influenza, Brazil: Influenza A(H1N1)pdm09 and other viral respiratory infections among fatal cases in pregnant and non-pregnant women – preliminary findings.
11:45 am – 12:00 pm Alberto Laguna Torres, NAMRU-6, Peru. The challenges of developing and maintaining a respiratory surveillance network.
12:00 – 12:15 pm Margot González, Instituto Mexicano del Seguro Social, México: Risk factors for hospitalization and death among influenza A (H1N1) patients, Mexico, 2009-2010.
12:15 pm – 1:45 pm Lunch
1:45 – 3:15 pm Session III: Influenza in the Americas: Seasonality, time series models, and disease burden
1:45 – 2:00 pm Walquiria Aparecida Ferreira de Almeida, Brazil Ministry of Health. Influenza surveillance in Brazil.
2:00 – 2:15 pm Aba Mahamat, MD, PhD, Cayenne General Hospital, Cayenne, French Guiana: Climatic drivers of influenza seasonality in French Guiana, 2006-2010.
2:15 – 2:30 pm Diego Garcilazo, Instituto Nacional de Enfermedades Respiratorias, Argentina: Time series analysis of pneumonia and influenza mortality: Argentina, 1980-2010.
2:30 – 2:45 pm Andreu Comas-Garcia, Instituto Nacional de Salud Publica, Mexico: Model for early detection of influenza outbreaks based on weekly reports of acute respiratory infections.
2:45 – 3:00 pm Po-Yung Cheng et al., CDC/PAHO: Influenza-associated Deaths in the Pan American Health Organization (PAHO) Region during Influenza Seasons and 2009 H1N1 Pandemic
3:00 – 3:15 pm Cécile Viboud, FIC, NIH: Burden of the 2009 pandemic in the United States compared to seasonal influenza
3:15 – 3:45 pm Coffee Break
3:45 – 4:15 pm Session IV: Influenza in swine and birds: Transmission and risks for humans
3:45 – 4:00 pm Martha Nelson, FIC, NIH, USA: Evolutionary dynamics of influenza viruses in North American swine.
4:00 – 4:15 pm Bruno Ghersi, NAMRU-6, Peru: Influenza and the human-animal interface in Peru.
4:15 – 5:30 pm Session V: Etiology of influenza and other respiratory diseases: Part I
4:15 – 4:30 pm Yeny Tinoco, NAMRU-6, Peru: Population-based active surveillance cohort studies for influenza in Peru.
4:30 – 4:45 pm Edwin Miranda, Instituto Nacional de Salud del Niño, Peru: Severity of pneumonia hospitalizations in children infected with the AH1N1/2009 influenza virus, Peru.
4:45 – 5:00 pm Bruno Alfredo, Insituto Nacional de Higiene, Ecuador: Surveillance of influenza virus and other causes of SARI in Ecuador.
5:00 – 5:15 pm Ana E. Arango, Universidad de Antioquia, Colombia: Monitoring influenza-like illness at a hospital in Medellin, Colombia.
5:15 – 5:30 pm Victoria Pando-Robles, Instituto Nacional de Salud, Mexico: Respiratory pathogens detection by RT-PCR and Mass-tag Multiplex PCR during the influenza A (H1N1 pdm) pandemic period, Mexico.
Day
2 - Tuesday, June 26: Scientific presentations
9:00 – 10:00 am Session VI: Etiology of influenza and other respiratory diseases: Part II.
9:00 - 9:15 am Dan Weinberger, FIC, NIH, USA: Interactions between pneumococcus and viral respiratory infections.
9:15 – 9:30am Víctor Raúl Ocaña Gutierrez , NAMRU-6, Peru, Sentinel Surveillance, epidemiological, clinical and virological features of influenza-like illness: Piura, 2000 to 2010.
9:30 – 9:45 am Ivette Lorenzana, Universidad Nacional Autónoma de Honduras,Tegucigalpa, Honduras: Surveillance of viral respiratory pathogens in Tegucigalpa, Honduras, 2006-2009.
9:45 – 10:00 am Sergio Jaramillo, Hospital Pablo Tobón Uribe, Colombia. Human metapneumovirus in hospitalized children, Medellín, Colombia.
10:00 – 10:30 am Coffee break
10:30 am – 12:15 pm Session VII: Genetic evolution of influenza and other respiratory viruses, Part I.
10:30 – 11:05 am Eddie Holmes, Penn State University and FIC, NIH, USA: Evolutionary dynamics of influenza viruses.
11:05 – 11:30 am Andrew Rambaut. University of Edinburgh, Scotland and FIC, NIH, USA: Antigenic and spatial evolution of influenza viruses.
11:30 – 11:45 am Elsa Baumeister, National Influenza Centre, INEI-ANLIS Carlos G Malbran, Argentina. Sequencing and phylogenetic analysis of influenza virus A(H3N2) and (H1N1)pdm09 viruses in Argentina, 2010-2011.
11:45 am – 12:00 pm Luis Felipe Paulin Paz, Instituto de Biotecnología UNAM, Mexico: Development of a microarray to determine the phylogenetic origin of the influenza A segmented genome.
12:00 – 12:15 pm Yi “Tany” Tan, FIC, NIH, USA: Epidemiological dynamics and phylogeography of influenza in southern China.
12:15 pm – 1:15 pm Lunch
1:15 – 2:30 pm Session VIII: Genetic evolution of influenza and other respiratory viruses, Part II.
1:15 – 1:30 pm Paola Cristina Resende, FIOCRUZ, Brazil: Molecular analyses of influenza A H1N1pdm09 viruses at the hemagglutinin gene in mild, severe, and death cases in Brazil from 2009 to 2011.
1:30 – 1:45 pm Maria de Lourdes Oliveira, Oswaldo Cruz Institute, National Reference Laboratory for Influenza, Brazil: Epidemiological and molecular patterns of influenza A(H1N1)pdm09 infections in Brazil: findings from the pandemic and post-pandemic periods.
1:45 – 2:00 pm José Correa-Basurto, ESM-IPN, Mexico: Outside-binding site mutations modify the active site shapes from neuraminidase of influenza A H1N1.
2:00 – 2:15 pm Marina Escalera Zamudio, IBT-UNAM, Mexico: Evolutionary dynamics of H3N2 influenza viruses in Mexico.
2:15 – 2:30 pm Karen Gallegos, College of Medicine, University of Cincinnati, USA. Neuraminidase assays for detection and differentiation of influenza viruses.
2:30 – 3:15 pm Session IX: Influenza vaccine issues.
2:30 – 2:45 pm Mark Miller, FIC, NIH, USA: Assessing the value of vaccination strategies for epidemic and pandemic influenza.
2:45 – 3:00 pm Isaias Raw, Butantan, Brazil: New developments in influenza vaccine production.
3:00 – 3:15 pm Juan Cristina, Facultad de Ciencias, Uruguay: Phylogenetic analysis of pandemic 2009 influenza A virus circulating in the South American region: genetic relations and vaccine strain match.
3:15 – 3:45 pm Coffee break
3:45 – 5:00 pm Session X: Roundtable discussions on influenza vaccine and surveillance issue in Latin America.
5:00 - 5:30 pm Closing remarks and opportunities for future collaboration
Day 3 - Wednesday, June 27: Technical Workshops
Topics covered by the technical workshops will include time-series and spatial analysis, wavelets, disease modeling, basic reproductive number estimation, phylogenetics, and data visualization. There will also be opportunities to work with NIH investigators individually and in small groups. SAS, Stata, and R code will also freely be available for distribution.
9:00 - 10:30 am Wladimir Alonso and Dan Weinberger, FIC, USA: Practical in time-series and spatial analysis methodologies and tools, visualization of data.
10:30 - 11:00 am Coffee break
11:00 am - 12:00 pm Gerardo Chowell and Cecile Viboud, FIC, USA: Reproduction number estimation and disease modeling.
12:00 - 1:30 pm Lunch
1:30 - 2:30 pm Eddie Holmes, FIC, USA: Phylogenetics 101.
2:30 - 3:00 pm Coffee break
3:00 - 4:00 pm Andrew Rambaut, FIC, USA: Introduction to the BEAST software package for Bayesian methods in phylogenetics.
4:00 pm - 5:30 pm Dataset presentations by participants (3 minutes each)
Day
4 - Thursday, June 28: Technical Workshops
9:00 – 10:00 am Hands-on tutorials, small group collaboration, one-on-one instruction
10:00 - 10:30 am Coffee break
12:30 - 1:30 pm Lunch
1:30 - 3:00 pm Hands-on tutorials, small group collaboration, one-on-one instruction
3:00 - 3:30 pm Coffee break
3:30 - 5:00 pm Hands-on tutorials, small group collaboration, one-on-one instruction
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MISMS Workshops |
Workshops
for epidemiologists and virologists led by the US National
Institutes of Health Fogarty International Center
Following
the meeting, a workshop describing the methodology to evaluate vital statistics,
virological, genomic and economic data to describe influenza disease burden and
inform policy will be held. It will consist of small-group sessions designed for epidemiologists, virologists, and policy-makers who are interested in evaluating datasets that can be brought
to the meeting for further analysis. Workshops will concentrate on methodologies
to evaluate time-series data for regional or national analysis of influenza disease
burden, assessments of control programs, and evolution of influenza viruses. Participants
will have the opportunity to learn analytical tools that can be applied to national datasets
and also to formulate further collaborations on bi-national and multinational studies.
Please note that participation in workshop sessions will
be limited and will be based on submitted dataset descriptions that participants may want to further analyze.
It
is highly recommended, but not required, that participants in the workshop bring:
- a laptop with statistical analysis software (i.e. SAS, STATA, or R)
- an influenza
dataset (vital statistics data, influenza isolate data, and vaccine coverage)preferred, but not required
Individuals
who attend the workshop will have the opportunity to learn about:
- time series
analysis
- spatial / temporal relationships
- influenza genomics tools
- data management issues
- SAS / Stata / R code
- strategies for evaluating vaccine benefits in a country using mortality data
- long-lasting research and surveillance collaborations
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If you would like more information about this meeting or about MISMS, please contact us at ficmisms@mail.nih.gov.
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